Big Picture Science

What’s it all about? And we mean ALL. What makes up this vast sprawling cosmos? Why does it exist? Why do we exist? Why is there something rather than nothing? Ow, my head hurts! For possible answers, we travel to the moment after the Big Bang and discover all that came into being in those few minutes after the great flash: time, space, matter, and light. Plus, the bizarre stuff that makes up the bulk of the universe: dark energy and dark matter. Also, what we set in motion with the invention of the light blub. How artificial light lit up our homes, our cities and – inadvertently – our skies. Guests: Sean Carroll - Theoretical physicist at California Institute of Technology Leonard Susskind - Theoretical physicist, Stanford University Jane Brox - Author of Brilliant: The Evolution of Artificial Light Peter Fisher - Physicist, Massachusetts Institute of Technology Descripción en español First aired September 6, 2010 Learn more about your ad choices. Visit megaphone.fm/adchoices

Wait! Before you step outside... is it Friday the 13th? Any black cats prowling around? Broken a mirror lately? Homo sapiens are a superstitious lot. Find out why our brains are wired for irrational belief. Plus, from the 2012-end-of-the-world prophesy to colliding planets - why some people believe the universe is out to get ‘em. Also, Brains on Vacation takes on a challenge to relativity and our Hollywood skeptic has doubts about exorcism. It’s enough to make your head spin on Skeptic Check… but don’t take our word for it! Guests: Bruce Hood - Cognitive scientist at the University of Bristol in the U.K. and author of The Science of Superstition: How the Developing Brain Creates Supernatural Beliefs David Morrison - Director of the Carl Sagan Center for The Study of Life in The Universe at the SETI Institute and keeper of the NASA website Ask an Astrobiologist Martin Snow - Research Scientist, Laboratory for Atmospheric and Space Physics at the University of Colorado at Boulder Jim Underdown - Exec

Have you lost your senses? You’ll find them everywhere you look. Sensors respond to external stimuli – light, sound, temperature and much else – to help us make sense (ha!) of our universe. And more are on their way. “Ubiquitous sensing” is the term that describes a world blanketed by tiny sensors: on bridges, in paint and medicine bottles, and even in our brains! Discover where you’ll find sensors next. And, has the world’s largest detection device found the elusive particle that will help explain the universe? Where are you, Higgsy-wiggsy? Also, out-of-this world sensors have detected a possibly Earth-like planet. What’s next for the Kepler planet-hunters? Plus, DIY sensor kits, and, if computers can do all that, why can’t we send the odor of, say, freshly-baked bread over the Internet? The case for a smell-o-meter. Guests: Frank Close - Physicist at Oxford University, author of The Infinity Puzzle: Quantum Field Theory and the Hunt for an Orderly Universe Jan Rabaey - Professor of Electrical Engineeri

The term “bird flu” is a misnomer, scientists say, because almost all human influenza originates in our feathered friends. How it lands in you and spreads is another matter … Hear what it takes for a virus to go global, from a virus hunter who plans to stop epidemics in their tiny DNA tracks with an innovative global surveillance system. Also, why your genome is littered with fossil viruses of the past … the two largest viruses discovered so far, Mimi and Mega, square off … and, what it takes for ideas to “go viral.” Guests: Nathan Wolfe - Viral Ecologist, Director of the Global Viral Forecasting Initiative Robert Gifford - Evolutionary virologist, Aaron Diamond AIDS Research Center at Rockefeller University Vincent Racaniello - Virologist at Columbia University’s College of Physicians and Surgeons, host of the podcast, “This Week in Microbiology,” and author of the “Virology Blog” Bill Wasik - Senior Editor at Wired, author of And Then There's This: How Stories Live and Die in Viral Culture Descr

Mom and apple pie. Computers and silicon. Martians and death rays. Some things just go together naturally. But how about science and politics? Science and religion? Science and fiction? These pairings are often unnatural and contentious … but they don’t have to be. Discover how science can team up with other endeavors in productive, if surprising, symbiosis. Meet a particle physicist, turned U.S. Congressman, who calls for more scientists on Capitol Hill. Also, a tour of the Golden Age of Islamic Science. Plus, scientists named Elmo and Super Grover 2.0 teach small children to conduct experiments with the help of chickens and dancing penguins. And, it’s not quite science but it’s not entirely fiction either: how sci-fi helps shape our cultural debates about the future. Guests: Bill Foster - Physicist and former U.S. representative from Illinois Carol-Lynn Parente - Executive Producer, Sesame Street Ranjana Mehra - Docent at The Tech Museum, San Jose, California Brooks Peck - Curator, EMP Museum, Seat

There’s no harm talking to your houseplant, but will your chatter really help it grow? We look at various biological claims, from whether plants feel pain to the ability of cats to predict earthquakes. Feline forecasters, anyone? Also, when does understanding biology have important implications for health and policy? The arguments for and against genetically modified foods, and the danger of “pox parties” as a replacement for childhood vaccination. Plus, the history and current state of scientific literacy in the United States. When did we stop trusting science? Guests: Andy Michael - Seismologist with the U.S. Geological Survey in Menlo Park, California Ron Lindsay - President of the Center for Inquiry, headquartered in Amherst, NY Steven Novella - Clinical neurologist and Director of General Neurology at Yale University School of Medicine; host of the Skeptics Guide to the Universe podcast Shawn Lawrence Otto - Author of Fool Me Twice: Fighting the Assault on Science in America Chelsea Specht -

Wish you could ditch computers? There’s no escape button for that. Computers are not only a part of your daily grind, they may soon be a part of you. We’ll hear from the world’s first cyborg about why we should make nice in our arms race with machines. Also, the secret behind the extraordinary breakthroughs that DARPA scientists are making – from building autonomous cars to wiring robotic surgeons. Plus, making space for humans… and their bodily functions: the engineering tricks of toiletry. And, a carbon-based astronaut on the view of Earth from orbit. Guests: Kevin Warwick - Professor of Cybernetics at University of Reading in the U.K. Santiago Bilinkis - Student at the Singularity University Mary Roach - Writer and author of Packing for Mars: The Curious Science of Life in the Void Tom Jones - United States astronaut, space consultant, and veteran of four Space Shuttle flights Michael Belfiore - Space and Technology writer, and author of The Department of Mad Scientists: How DARPA Is Remaking O

Think small! Microbes are tinier than the dot at the end of this sentence, yet they can make humans sicker than dogs, dogs sicker than humans, jump from animal to human and keep scientists guessing when and where the next disease will appear. Discover how doctors diagnosed one man’s mysterious infection, the role that animals play as hosts for disease, and why the rate of emerging diseases is increasing worldwide. Also, why your kitchen is a biosafety hazard, and how the Human Microbiome Project will tally all the microbes on – and in - you. Plus, the extreme places on Earth where microbes thrive and what it suggests for the existence of alien life. And, how one strain of bacteria helped a farmer grow a pumpkin the weight of a small car! Guests: Peter Hudson - Biologist, Director of Life Sciences at Penn State University Peter Krause - Senior research scientist at the Yale School of Public Health Durland Fish - Epidemiologist at the Yale School of Public Health. Information on his Lyme disease app Da

“Making space for everyone” could be NASA’s motto. But as commercial spaceships get ready to blast off, that populist idea is being tested. Space cowboys in the private sector say they’re the ones who can provide unfettered access to space, for tourists and scientists alike. Meet a scientist who already has a ticket to ride on SpaceShip Two and discover what he hopes to learn about asteroids during his five minutes of weightlessness. Plus, NASA in motion: it’s back to the moon as the GRAIL mission probes the interior of our lovely lunar satellite. Also, can you dig it? The rover Curiosity can. It’s headed to Mars to hunt for clues to alien life … with a jackhammer. Also, as the Hubble Space Telescope shuts down, the James Webb Space Telescope revs up. Or does it? The telescope is designed to study the birth of galaxies and hunt for evidence of water on far away worlds. But will Congress pull the plug? Guests: James Oberg - former Space Shuttle Mission Control engineer, and space expert Maria Zuber - Plane

What you can’t see … can make you sick. Humans have been battling viruses and bacteria since the beginning of time. The malaria parasite has been keeping deadly company with us for 500,000 years. King Tut had it and so did Julius Caesar. What’s keeping this bug going today? Also, how disease almost halted the most ambitious engineering project in the world … how elite disease detectives puzzle out perplexing epidemics … And – could tiny bugs from spaaace, ace, ace be our ancestors? Guests: Sonia Shah - Author of The Fever: How Malaria Has Ruled Humankind for 500,000 Years Michael Conniff - Historian, director of Global Studies at San Jose State University, and author of Black Labor on a White Canal: Panama, 1904-1981 (Pitt Latin American Series) Mark Pendergrast - Author of Inside the Outbreaks: The Elite Medical Detectives of the Epidemic Intelligence Service Robert Zubrin - President of the Mars Society Descripción en español First aired August 2, 2010 Learn more about your ad choices. Visit meg

Calling all pessimists! Your brain is wired for optimism! Yes, deep down, we’re all Pollyannas. So wipe that scowl off your face and discover the evolutionary advantage of thinking positive. Also, enjoy other smile-inducing research suggesting that if you crave happiness, you should do the opposite of what your brain tells you to do. Plus, why a “well-being index” may replace Dow Jones as a metric for success … a Twitter study that predicts your next good mood … and whether our furry and finned animal friends can experience joy. Guests: Frank Drake - Astronomer and author of the Drake Equation Tali Sharot - Cognitive neuroscientist at the Wellcome Trust Centre for Neuroimaging at the University College London and the author of The Optimism Bias: A Tour of the Irrationally Positive Brain Michael Macy - Sociologist at Cornell University His team’s Twitter study: http://timeu.se/ Carol Graham - Economist at the Brookings Institution and author of The Pursuit of Happiness: An Economy of Well-Being

Zombies, aliens, Bigfoot, oh my!! We've covered - or rather uncovered - them all and more on Skeptic Check, our monthly look of critical thinking. And now we've collected enough strange encounters to assemble a sordid retrospective of sorts. Sharpen your brain, it's Skeptic Check, Beast Of. But don't take our word for it! Guests: Phil Plait - Skeptic and keeper of Discover Magazine’s blog, badastronomy.com Bruce Hood - Cognitive scientist at the University of Bristol in the U.K. and author of The Science of Superstition: How the Developing Brain Creates Supernatural Beliefs Susan Jacoby - Author of The Age of American Unreason Steve Silberman - Contributing editor, Wired Magazine, author of “The Placebo Problem” in the September 2009 issue Mary Pope-Handy - Estate Agent, Silicon Valley and keeper of the website hauntedrealestate.com Jim Underdown - Executive Director, Center for Inquiry, West – Los Angeles Paul Offit - Pediatrician, Chief of Infectious Diseases at Children’s Hospital of Phil

Shh - can you keep it down? Nope. Not unless you want to do away with civilization. Our buzzing, humming, whirling, machine-driven world is a poster child for technological progress, right? As is hearing loss. It’s driven one man to search the world for silence. We’ll hear what he didn’t hear, and what Einstein predicted we should hear in deep space, where gravitational waves may reveal the hidden sounds of the universe, including the birth of black holes. Guests: George Foy - Author of Zero Decibels: The Quest for Absolute Silence Garret Keizer - Author of The Unwanted Sound of Everything We Want Craig Hogan - Director for Particle Astrophysics at the Fermi National Accelerator Laboratory Descripción en español First aired July 5, 2010 Learn more about your ad choices. Visit megaphone.fm/adchoices

Anyone who does gardening knows that life is tough. It’s also ancient – the first living things appeared on this planet nearly as soon as our world was habitable. We consider life on real worlds – like Earth and Mars – as well as fictional ones, such as the desert planet from the movie “Dune”. We’ll hear about a new scheme to find Martians, and practical approaches to coping with climate change. And is Pluto seeking revenge? The unmasking of a fourth moon around this former planet! We’re making some lively discoveries in Seth’s Tool Shed on Big Picture Science. Guests: Philip Duffy - Physicist and senior scientist at Lawrence Livermore National Laboratory Kevin Zahnle - Planetary scientist at the NASA Ames Research Center David Summers - Astrobiologist at the SETI Institute Christopher Carr - Researcher in the Department of Earth, Atmospheric, and Planetary Sciences at the Massachusetts Institute of Technology Mark Showalter - Research scientist at the SETI Institute Descripción en español Learn m

During the great age of exploration men risked their lives to set foot upon unknown lands, whether in the humid jungles of Peru or on the barren ice cap of the South Pole. We'll hear those dramatic tales… … but also where modern exploration is taking us. Could it be to the deepest, darkest part of the sea? Or to space? Discover how to build a space suit that will let you move like an athlete on Mars. Also, why some say that the ultimate frontier requires no packing and no travel: voyages into the human brain. Guests: Dava Newman - Professor of Aeronautics and Astronautics Engineering Systems, MIT David Eagleman - Neuroscientist, Baylor College of Medicine and author of Incognito: The Secret Lives of the Brain Mark Adams - Author of Turn Right at Machu Picchu Edward Larson - Author of An Empire of Ice: Scott, Shackleton and the Heroic Age of Antarctic Science Liz Taylor - President, Deep Ocean Exploration and Research, Alameda, CA Descripción en español Learn more about your ad choices. Visit meg

The recipe for being a scientist was easy in the old days… just be born into a rich family, have an interest in nature and plenty of time to indulge yourself. But are the days of gentlemen scientists over? Maybe not. We go to the Maker Faire and check out how small-scale projects have big-scale ambitions. Also, how everyday experience often tells us something profound about the universe. Guests: Spencer Weart – Former director of the Center for the History of Physics, at the American Institute of Physics Tim Russ – Actor, and the character Tuvok on Star Trek Voyager Marcus Chown – Science writer and author of The Matchbox That Ate a Forty-Ton Truck: What Everyday Things Tell Us About the Universe Learn more about your ad choices. Visit megaphone.fm/adchoices

An ant … can’t … move a rubber tree plant… but the colony can. As a group, ants are an efficient, organized, can-do bunch. And a model for humans trying to manage complex systems. Find out about the eerie collective intelligence of animals, and how an MIT researcher is hoping to put humans to work collaboratively to solve problems like climate change. Also … hear how research into flocking behavior helps Hollywood film a herd of stampeding dinosaurs. Guests: Steve Strogatz - Applied mathematician at Cornell University and author of Sync: How Order Emerges From Chaos In the Universe, Nature, and Daily Life Craig Reynolds - Senior researcher for Sony Computer Entertainment Thomas Malone - Director of the Center for Collective Intelligence at MIT Iain Couzin - Biologist at Princeton University Descripción en español Originally aired June 21, 2010 Learn more about your ad choices. Visit megaphone.fm/adchoices

It’s been ten years since the fall of the Twin Towers, but some still believe that the attack was an inside job. They’re not the only ones to buy into a conspiratorial view of world events. Others deny President Obama’s American birth… link autism with vaccines… and even claim that the fluo ride in our drinking water is there to control our minds. Is it the truth - or the fringe groups - that are “out there?” Find out why some tinfoil hat ideas never go away. Also, the roots of rational argument: did our brains evolve to seek the truth… or just win arguments? It’s Skeptic Check… but don’t take our word for it! Guests: Jonathan Kay - Managing editor of National Post in Canada and author of Among the Truthers: A Journey Through America’s Growing Conspiracist Underground Michael Shermer - Founding Publisher of Skeptic Magazine and author of The Believing Brain: From Ghosts and Gods to Politics and Conspiracies – How We Construct Beliefs and Reinforce Them As Truths Phil Plait - Skeptic and keeper of Disc

Genes – what are they good for? Absolutely… something. But not everything. Your “genius” genes need to be turned on – and your environment determines that. Find out how to unleash your inner-Einstein, and what scientists learned from studying the famous physicist’s brain. Also, the bizarre notion that your children inherit not just your genes, but also the consequences of your habits – smoking, stress, diet, and other behaviors that turn the genes on. Plus Francis Collins on affordable personal genomes, and a man who decoded his own DNA in under a week. Guests: Francis Collins - Geneticist, Director of the National Institutes of Health David Shenk - Journalist, and author of The Genius in All of Us: Why Everything You’ve Been Told About Genetics, Talent and IQ is Wrong Stephen Quake - Biophysicist, Stanford University Dean Falk - Anthropologist and Senior Scholar at the School For Advanced Research in Santa Fe, New Mexico Descripción en español Learn more about your ad choices. Visit megaphone.fm/ad

Live forever? Both cancer cells and stem cells can make a claim to immortality. Left unchecked, tumors will grow indefinitely. And stem cells offer the promise of non-stop rejuvenation. We’ll find out whether the surprising discovery of stem cells in the brain really can keep our thinking organ young. And we’ll hear the remarkable story of Henrietta Lacks, the woman who unwittingly donated tissue to science in 1951, and whose cancer cells are still grown in laboratories around the world today. Guests: Rebecca Skloot - Journalist and author of The Immortal Life of Henrietta Lacks Fred Gage - Neurobiologist at the Salk Institute Randy Schekman - Molecular and cell biologist at the University of California, Berkeley Descripción en español Learn more about your ad choices. Visit megaphone.fm/adchoices