Synopsis
Dr Adam Rutherford and guests illuminate the mysteries and challenge the controversies behind the science that's changing our world.
Episodes
-
Democracy in Space
08/02/2018 Duration: 28minThis week a US based billionaire launched a giant space rocket and sent a car vaguely in the direction of Mars. As a space mission it was to say the least unconventional, and for those involved in promoting space science it presents a quandary. Is such a mission largely a publicity stunt or is it useful for engaging people in the potential of space exploration? Gareth Mitchell looks at one project which enables schoolchildren to programme computers on the International Space Station and he talks to the European Space Agency about why a rock concert might be a good avenue for exploring space science. As more and more of our everyday lives are conducted online we ask what are the cyber-security threats of today, and how can science be used to counter them. Do we now need new kinds of science to locate, understand and stop new kinds of threat? Can bat science help human ageing research? New findings have show that some long lived bat species do not age in the same way as other mammals. They don't even seem to po
-
Scientists on Trial
01/02/2018 Duration: 32minIn 2016 there was an attempted coup in Turkey. This led to many people who the government saw as opposition figures being sacked from their jobs and in some cases held without trial. They include prominent intellectuals, medics and scientists. In recent days there has been a similar crackdown on people voicing criticism of Turkey's current military actions in Syria. Stephen Reichter, Professor of Psychology at St Andrews University has been to Turkey to observe the trial of one of his former colleagues. He tells us what he saw and discusses the wider issues for science.It's the 60 years since the launch of Explorer 1 and the discovery of the Van Allen Belts. This was the satellite the US launched in response to Sputnik. However unlike Sputnik it did undertake scientific exploration, its findings have been significant for every space mission that followed.Using DNA sequencing scientists have found that the 'Two Brothers' mummies at the Manchester Museum have different fathers so are, in fact, half-brothers. Kh
-
Did typhoid kill the Aztecs, DNA stored in Bitcoin, Glow-in-the-dark plants and levitating humans
25/01/2018 Duration: 28minWhat killed the Aztecs? In some areas of the Americas, as many as 95% of the indigenous population died of diseases brought in by the discoverers of the New World. Pandemics hit the population who had little immunity to diseases carried by people and livestock. One outbreak responsible for killing millions started in 1545 and was locally called 'cocoliztli'. But for the last 500 years, exactly what this deadly disease was has remained a mystery. Adam talks to Johannes Krause of the Max Planck Institute who has analysed the teeth of 10 individuals from a mass grave for pathogens and found remnants of typhoid fever DNA. Could this be, in part, responsible for the deaths of millions? Historian Caroline Dodds Pennock from the University of Sheffield discusses the difficulties of knowing for definite what killed so many millions of people. In 2015, Nick Goldman issued a challenge. If anyone could decode the information he had stored on some DNA by 21st January 2018, they could win a bitcoin. When Nick bought the b
-
African swine fever, Oil spill update, CRISPR gene editing, Rat eradication in New Zealand, Chimp kin recognition
18/01/2018 Duration: 28minAfrican Swine fever is deadly to pigs and is spreading west from Russia across Europe. The virus that causes it is very resilient and can stick around on clothing, hay and in infected pork products for as long as 150 days. Biosecurity is crucial to preventing its arrival in the UK. If just one pig eats some infected meat from discarded human food the disease could quickly spread causing thousands of pigs to be culled and costing the industry millions. But what is the current progress on developing a vaccine? Adam talks to virologist Professor Jonathan Ball of Nottingham University and Zoe Davies from the National Pig Association. Simon Boxall from Southampton Oceanography Centre gives an update on the sinking of the oil tanker Sanchi and its environmental impact. CRISPR is a revolutionary gene editing technique which can modify DNA and has the potential to correct genetic errors in a range of human diseases - even cancer. The technique has only been around for a few years but is already being talked about as
-
Sanchi oil tanker, Gut gas-monitoring pill and Chimpanzee portraits
11/01/2018 Duration: 27minAfter the Sanchi oil tanker collided with another ship it discharged its cargo of 1 million barrels of condensate oil. This could cause one of the biggest oil disasters in 25 years. What is condensate, can it be cleaned up and how toxic to marine life is it if large amounts of it leak or the tanker sinks? Adam talks to Simon Boxall from Southampton Oceanography Centre. A long-held belief that babies look more like their fathers is being put to the test by scientists at St Andrews University. They are launching an on-line citizen science experiment asking members of the public to see if they can tell from a group of chimps which are the close relations. Geoff Marsh takes the test and talks to researcher Cat Hobaiter about why it might be advantageous for a baby primate to look like its father more than its mother and what they hope to learn from humans' ability to recognise chimp family trees. A new swallow-able, electronic pill that sniffs out the gas produced in your gut could be the answer to accurately dia
-
Tabby's Star, Space 2018, Mosquito sounds, C diff and food additive link
04/01/2018 Duration: 32minAdam Rutherford talks to astronomer Tabetha Boyajian at Louisiana State University about the wierd star that's perplexed astronomers since its discovery two years ago. KIC 8462852 has the unique habit of intermittently and sometimes dramatically dimming and then brightening. Some scientists even suggested vast alien megastructures around the star might be the explanation. After twenty months of almost continuous observation, Professor Boyajian has much more information about what the star is doing. But the big mystery hasn't gone away.BBC News science correspondent Jonathan Amos joins Adam to share some highlights in space exploration for the coming 12 months.Zoologists and engineers at the University of Oxford are developing an app that identifies one species of mosquito from another by analysing the sounds their rapid wing beats make. Graihagh Jackson visits Marianne Sinka at the Zoology Department to listen to her collection of mosquito songs.Did the widespread introduction of the food additive trehalose f
-
Ancient DNA and Human Evolution
28/12/2017 Duration: 34minTwenty years ago, a revolution in the study of human evolution began. A team in Leipzig in Germany successfully extracted DNA from the bones of a Neanderthal man who died about 40,000 years ago. Thirteen years later, the same group unveiled the first complete genome sequence of another Neanderthal individual. Last year, they announced they'd retrieved DNA from much oldest archaic human bones, more than 400,000 years old.Adam Rutherford talks to Svante Paabo, the scientist has led these remarkable achievements. Professor Paabo and his colleague Janet Kelso at the Max Planck Institute of Biological Anthropology in Leipzig discuss the genes in many European people alive today that originated in Neanderthals and were passed to modern humans when the two species interbred. Adam also speaks to Johannes Krause who worked on the Neanderthal genome project in Leipzig but is now director of the Max Planck Institute of the Science of Human History. His latest research adds a new layer of intrigue and complexity to the r
-
Antisense RNA therapy, Fossils vs Trump, Printing mini-kidneys, Electric eel power
21/12/2017 Duration: 29minPromising results from a small clinical trial of Huntingdon's disease patients have led to RNA-directed therapy such as antisense RNA being hailed as possibly a turning point in the treatment of neurodegenerative diseases. Adam Rutherford discusses this class of drugs with Heidi Ledford of Nature News.At the beginning of the month, Donald Trump decreed that two national monument landscapes be drastically down-sized. Strict protections against exploitation were removed from vast tracts of land bearing some of the world's most important fossil bearing strata. President of the Society of Vertebrate Paleontologists, Professor David Polly explains why his organisation is now suing Trump.At Harvard University, bioengineers are growing parts of functioning kidneys in small chips using a form of 3D printing. Jennifer Lewis' lab is doing this to learn how kidneys function and explore the possible therapeutic applications of the mini-kidneys-in-a-chip. Roland Pease visits the team at work.The electric eel can deliver a
-
The Future of Coral Reefs, Little Foot, Arthur C Clarke
14/12/2017 Duration: 34minOxford is hosting the European Coral Reef Symposium this week. Climate change is seen as the number one threat to the future of coral reefs. Adam talks to Morgan Pratchett of James Cook University about the two recent coral bleaching events that hit the Great Barrier Reef, and to Barbara Brown of Newcastle University about the potential for coral species to adapt to warmer seas.After twenty years of excavation and preparation, the most complete fossil skeleton of an Australopithecine has been unveiled to the public in South Africa. Its discoverer Ron Clarke explains its significance for understanding human evolution.December 16th is the 100th anniversary of Arthur C Clarke. Science writer Marcus Chown and cultural journalist Samira Ahmed join Adam to discuss Clarke's visions and works of science fiction.
-
Trophy hunting, Gene drives, Nuclear lightning, Peregrine falcons and drones
07/12/2017 Duration: 31minTrophy hunters are always after the lion with the largest darkest name and the stag with the most impressive antlers. Research by Rob Knell at Queen Mary University of London finds that removing a small proportion of these top males can drive whole populations to extinction, if their environment is changing.Gene drive is a new genetic technology that could be used to eradicate populations of species of 'pest' animals. The Roslin Institute in Edinburgh has just announced it is to begin research on gene drives to control rat and mouse populations. The Institute's Bruce Whitelaw and Simon Lillico explain how the approach would work and argue that it would be humane compared to traditional methods of vermin control. However there are concerns about its potential ecological consequences - namely the risk of female infertility in the targeted species spreading without no geographical limits. Kevin Esvelt of MIT voices his reservations. Bruce Whitelaw outlines how future research aims to bring gene drives under more
-
Prehistoric Strong Women, Semi-synthetic Life, Listener Feedback, Artificial Superintelligence
30/11/2017 Duration: 38minMore than 5,000 years of heavy agricultural labour by women can be read from the bones found in ancient cemeteries from the Neolithic to Iron Age times. Cambridge University anthropologist Alison Macintosh compared the arm bone dimensions and strength of women from these times with those of modern female athletes such as runners to rowers. Her conclusion is that average upper body strength of women through the Neolithic to the Iron age times exceeded that of today's semi-elite female rowers.A laboratory at the Scripps Research Institute have created a semi-synthetic bacterium with two new man-made genetic letters in its DNA, in addition to the natural four A, G, T and C. What's more, the engineered microbe can use its enhanced genetic alphabet to build synthetic amino acids into the proteins it makes. Chemist Floyd Romesberg talks to Adam Rutherford about what we can learn from his team's extraordinary feat of synthetic biotechnology, what we might gain from it and why, in his opinion, we've no need to be wor
-
Interstellar visitor, Svante Paabo, Synthetic biology, Plight of the Axolotl
23/11/2017 Duration: 34minOn 19th October, a mysterious object sped through our solar system. It was first spotted by astronomers with a telescope in Hawaii. Its trajectory and speed told of its interstellar origins. It is the first body to be detected from outside our solar system. Scientists are now publishing their papers on the enigmatic visitor. They estimate that it was about 400 metres long and bizarrely elongated in shape. Adam Rutherford talks to astronomer Alan Fitzsimmons of Queens University in Belfast. Twenty years ago, geneticist Svante Paabo began a revolution in human evolution science when he extracted fragments of DNA from the 40,000 year old bone of a Neanderthal. Among other first, he went onto sequence the entire genome sequence of Homo Neanderthalenisis. Professor Paabo was in the UK this week at a conference on DNA and human evolution at the Wellcome Genome Campus to mark the anniversary. He tells Adam about one of the new directions of research for him now.What does the future hold for synthetic biology? Who wi
-
Can we forecast earthquakes?, Britain's space race rocket Skylark, Francis Galton
16/11/2017 Duration: 36minWhat might the length of the day have to do with the likelihood of destructive earthquakes around the world? According to Professors Rebecca Bendick and Roger Bilham, there's a correlation between changes in the rate at which the Earth rotates and the incidence of earthquakes of Magnitude 7 and above. The rotation speed of the planet increases and decreases over periods of years and decades. From their research, the earth scientists say that there's an substantial increase in the number of powerful earthquakes around the world five years after the Earth attains a peak in its spin speed and enters a period of slow down. The difference in day length is tiny but it is enough, say the researchers, to trigger already stressed faults in the crust to move sooner than later.In the year that the Soviet Union launched Sputnik into orbit, the UK launched its own rocket into the Space Race. 1957 saw the launch of the first Skylark space rocket. Inside Science talks to two veterans of the Skylark programme - Professors Jo
-
Boy gets New Skin, The York Gospels, Stephen Hawking's Thesis
09/11/2017 Duration: 32minResearchers in Italy and Germany have saved the life of a boy with a life threatening genetic skin disease, using a combination of stem cell and gene therapy. 7 year old Hassan had lost 60% of his protective epidermis because of the condition, junctional epidermolysis bullosa. The severe blistering and consequent bacterial infections put his life in imminent danger. In a final attempt to save him, the scientists took a small area of unblistered epidermis from his body, separated the constituent skin cells and then engineered them with a normal version of the gene that was malfunctioning in Hassan's body. Sheets of healthy epidermis of an area of about one square metre were then grown in culture, and then grafted onto 80% of his body. Hassan is now living a normal life, back at school, playing football. Lead researcher Michele de Luca describes the remarkable recovery and Fiona Watt, director of the Centre for Stem Cell and Regenerative Medicine at Kings College London, explains how the procedure worked.Scient
-
Climate Change and Health; Moth Snow Storm Feedback; Whale Brain Evolution; Pharoah's Serpent
02/11/2017 Duration: 34minAdam Rutherford talks to researchers on a major global study that aimed to quantify how climate change has already damaged the health of millions of people. Hugh Montgomery is the co-chair of the Lancet Countdown report and says that climate change is the largest single threat to global health. Climate scientist Peter Cox talks about his stark findings on the increase in the number of vulnerable people exposed to heat waves between now and the turn of the century.We hear anecdotes and concerns from listeners following our item last week on the catastrophic decline in flying insects in the last quarter century and the disappearance of moth snow storms.What can the social lives and brains of whales and dolphins tell us about the evolution of our species cognitive capacities and white matter? Adam talks to Susanne Shultz of the University of Manchester.Everyone's favourite indoor firework, the Pharoah's Serpent, is under scientific scrutiny from chemists Tom Miller and Andrea Sella at University College London.
-
Insects disappearing, DNA Biosensor, Dog faces, Bandit dinosaur
26/10/2017 Duration: 33minThe total biomass of flying insects in the environment has decreased by 75% in the last quarter of a century. That's the conclusion of research published at the end of last week in the journal PLOS One. The discovery, made in Germany, has shocked many, but should we in the UK be worried too? The answer is yes, according to Adam Rutherford's guests Dave Goulson, professor of biology at the University of Sussex, and Michael McCarthy, environmental journalist and author of 'The Moth Snow Storm.'The speed and ease of precise infection diagnosis could be transformed by synthetic biologists at Imperial College, London. Paul Freemont tells Adam about a simple DNA biosensor that turns green in the presence of a pneumonia-causing bacterium that is a particular problem for people with Cystic Fibrosis. He adds that the technology is adaptable to any kind of bacteria and may also aid efforts to curb the spread of antibiotic resistance.When dogs know you are looking at them, they ramp up the expressiveness of their faces.
-
Colliding Neutron Stars, Krakatoa, Centigrade vs Celsius
19/10/2017 Duration: 34minAdam Rutherford talks to astrophysicists about the astronomical discovery of the year, if not the last couple of decades: the collision of two neutron stars and the cosmic gold-forging aftermath. The discovery of this long-hypothesized event on 17th August came from the much awaited marriage of the capabilities of the gravitational wave detectors LIGO and Virgo with those of ground-based and space-based telescopes. Samaya Nissanke of Radboud University, Sheila Rowan of the University of Glasgow and Nial Tanvir of the University of Leicester take Inside Science through the story.What made the infamous 1883 eruption of Krakatoa so devastating? Roland Pease meets the earth scientists trying to answer the question by recreating in the lab the conditions under the volcano prior to the eruption.Following a temperature-related faux pas by Adam in the last episode, Michael de Podesta of the National Physical Laboratory explains the difference between Celsius and Centigrade.Producer: Andrew Luck-Baker.
-
HiQuake, Plate Tectonics@50, Sonic Weapon Puzzle, The Chinese Typewriter
05/10/2017 Duration: 37minGareth Mitchell talks to Gillian Foulger of Durham University about HiQuake, the world's largest database of human-induced earthquakes. Professor Foulger and her colleagues have so far compiled close to 750 seismic events for which there are reasonable cases to be made for anthropogenic triggers. Triggers include mining operations, fossil fuel extraction, reservoir filling, skyscraper construction and tunnelling. Among the surprises is the fact that the US state of Oklahoma is more seismically active than California because of quakes and tremors set off by the local oil and gas industry. The theory of plate tectonics is 50 years old. It's as fundamental to understanding the Earth as evolution by natural selection is to understanding life. Roland Pease meets geologists such as Dan McKenzie, John Dewey and Xavier Le Pichon who played key roles in proving the hypothesis in the late 1960s.The United States has removed more than half of its diplomats from its embassy in Havana, Cuba. A signficant number of staff h
-
Gravity wave breakthrough, The antibiotic pipeline, Microbial waste recycling, Fausto - an AI opera
28/09/2017 Duration: 30minThe gravitational waves produced by two massive black holes colliding have for the first time been detected by three gravitational wave detectors. Professor Sheila Rowan of the University of Glasgow explains the importance of this new three way observation.The World Health organisation reports that there are too few new candidate antibiotics in the development pipelines to replace those becoming obsolete through the rapid spread of antibiotic resistance. Professor Willem van Shaik of the University of Birmingham and pharma-biotech analyst Dr Jack Scannell discuss where the problems and solutions might lie.Could bacteria recycle all of our waste? Waste disposal is a growing concern as nations run out of space and ecosystems are increasingly polluted. Microorganisms may hold the key for turning household waste into biodegradable plastic and perhaps one day even into food and basic chemical feedstocks. Hans Vesterhoff, Professor of Systems Biology at Amsterdam University is developing microbial networks with the
-
Cassini's finale; Science and Technology Select Committee; Crick's lecture; Cave acoustics
21/09/2017 Duration: 27minAfter last week's Inside Science's edition devoted to Cassini ended, the Cassini spaceship plunged into the atmosphere of Saturn, and became part of the planet it studied. But the project lives on, as the data and photos generated by Cassini right up until contact was lost will be studied and scrutinised for years to come. Linda Spilker is the Project Scientist for the Cassini mission. Adam Rutherford spoke to her to find out what was captured in the last few moments of Cassini's closest and fatal encounter with the ringed planet. The House of Commons has announced its Science and Technology Select Committee - the body of MPs that holds the Government to account on scientific matters, and offers advice on scientific issues of the day. Some controversy has followed, concerning the scientific credentials and the gender imbalance of the committee make-up so far. Norman Lamb, MP for North Norfolk was elected chair of the committee, and he came into the Inside Science studio to discuss the committee selection and