Nih Collaboratory

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Lesley Curtis speaks with Dr. Robert Califf, Head of Strategy and Policy at Verily Life Sciences and Google Health about whether the COVID-19 crisis can lead to reformation of the current healthcare delivery system. This discussion follows Dr. Califf's keynote presentation of a Grand Rounds Series titled Advances at the Intersection of Digital Health, Electronic Health Records, and Pragmatic Clinical Trials.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Leora Horwitz of NYU Langone Health about creating a Learning Health System through randomization.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Mitesh Patel of University of Pennsylvania about using nudges in a healthcare system to “steer medical decision-making toward higher value and improved patient outcomes.”

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Nigam Shah of Stanford University to discuss an informatics service called “Green Button,” which searches across diagnosis and procedure codes, concepts extracted from clinical notes, laboratory test results, vital signs, as well as visit types and duration of inpatient stays, to ultimately compare outcomes and guide practice.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Paul Harris to discuss REDCap integration with Fast Healthcare Interoperability Resources (FHIR). In the discussion, Harris covers past challenges of Electronic Health Record and Electronic Data Capture integration, progress in development of a new model, and current adopters of FHIR.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Drs. Rebecca Li and Frank Rockhold to discuss clinical trial data sharing and re-use. In the discussion, Li and Rockhold highlight benefits, potential fears, and the future of data sharing and open science as well as Vivli, a global clinical research data sharing platform.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Kevin Weinfurt sits down with Craig Lipset to discuss the role and impact of digital in trials and its various roles. In the discussion, Lipset highlights displacement and its impact on traditional research models, the concept of digital twins, and opportunities that stakeholders have to address the barriers that exist for to meaningful adoption for of digital technologies in clinical research.

Dr. Murali Doraiswamy discusses potential uses of artificial intelligence technologies in the field of mental health. (Audio track of the webinar.)

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Rob Mentz to discuss balancing Good Clinical Practice Guidance and Pragmatic Trials in the Learning Health System. In the discussion, Dr. Mentz covers key challenges with good clinical practice (GCP), input from Dr. Rob Califf and others, and suggestions on how the scientific community should address the evolution of GCP versus the evolution of clinical trials.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez sits down with Dr. Elise Berliner and Michelle Leavy to discuss the Development of Harmonized Outcome Measures for Use in Research and Clinical Practice. In the discussion, Dr. Berliner and Leavy explain the outcome measures framework and harmonizing outcomes in specific clinical areas.

Podcast 21: The Pragmatic Airway Resuscitation Trial (PART) by NIH Collaboratory

Podcast 20: Perinatal Outcomes Associated with a Major Change in Gestational Diabetes Screening by NIH Collaboratory

Podcast 19: Validating a Computable Phenotype by NIH Collaboratory

Podcast 18: Data Linkage Within, Across, and Beyond PCORnet by NIH Collaboratory

Renee Mitchell, Terrie Reed, and Roseann White discuss the Medical Device Epidemiology Network’s RAPID and SPEED projects.

Podcast 16: Returning Individual Research Results to Participants by NIH Collaboratory

Steve Steinhubl, Director of Digital Media, Scripps RTI,discusses a digital & pragmatic clinical trial that explores under diagnosed Atrial Fibrillation in large health population.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Michelle Mello discusses a study she and Dr. Steven Goodman recently conducted to determine how clinical trial participants think about having their participant-level data widely shared. In her discussion with Dr. Lesley Curtis, Dr. Mello discusses study results, what she found most surprising, and how the study revealed takeaways for researchers and clinical trial sponsors. Study results are published in “Clinical Trial Participants’ Views of the Risks and Benefits of Data Sharing” in the New England Journal of Medicine.

Podcast 13: Rethinking University Research with State Data (Aaron McKethan, PhD) by NIH Collaboratory

Podcast 12: Exploring What is Possible with High-Quality Data. Examples from Flatiron Health by NIH Collaboratory