Empowered Patient Podcast
Tackling Rare Autoimmune Diseases with Novel Bispecific Antibodies with Kiran Nistala Zura Bio
- Author: Vários
- Narrator: Vários
- Publisher: Podcast
- Duration: 0:18:22
- More information
Informações:
Synopsis
Kiran Nistala, Chief Medical Officer and head of development at Zura Bio, describes how their novel molecules target multiple pathways to provide more effective treatments for patients with autoimmune diseases. This is particularly necessary for those with complex, heterogeneous manifestations not well addressed by current therapies. Zura Bio's novel molecules target rare diseases such as systemic sclerosis and hidradenitis suppurativa and show potential for use in combination with existing approaches. Kiran, "Developing bispecifics is a known, but it's quite a technical skill, and I think there are lots of reasons—first, bioengineering to get the right molecule. Secondly, you must also know how to design studies to show that both sides are doing what you expect of that molecule. So both pathways are being affected. And I guess you must also choose the right disease where you think those pathways are super important. So, we've been incredibly thoughtful in our approach- we haven't just jumped in, and some o