Nature Podcast

Engineering yeast to produce medicines, and the mechanism of anaesthetic action.In this episode:00:44 Making medicine with yeastThe tropane alkaloids are an important class of medicine, but they are produced agriculturally leaving them vulnerable to extreme weather and world events. Now, researchers have engineered yeast to produce these important molecules. Research Article: Srinivasan and Smolke06:36 CoronapodWe discuss the complex story of immunity to COVID-19, and how this may affect vaccine development. News Feature: What the immune response to the coronavirus says about the prospects for a vaccine16:33 Research HighlightsThe neurological reason for overindulgence, and the bacteria that harness copper electrodes. Research Highlight: The brain circuit that encourages eating for pleasure; Research Highlight: Microbes with mettle build their own electrical ‘wires’19:07 The molecular mechanisms of general anaestheticsDespite over a century of use, there’s a lot we don’t know about how anaesthetics function.