Trt Revolution Podcast

There are a lot of physicians who still believe that TRT will exacerbate prostate cancer, and that people on TRT can take AIs. What does research actually tell us about this? Why should you consider optimization? What is the relationship between sex hormone binding globulin and testosterone? On this episode, double board certified physician and PhD candidate, Dr. Nick Sakkas goes deep on these questions and provides insights backed by some interesting recent research. Testosterone induces cell apoptosis of prostate cancer and inhibits proliferation. -Dr. Nick Sakkas Three Takeaways You have to understand how SHBG is going to affect the testosterone molecularly before you do TRT. Undergoing TRT and taking an AI suppresses estrogen and puts you at an extreme risk of developing cardiac hypertrophy and organ damage in the long-term. On prostate cancer: low testosterone levels are associated with a poor prognosis.   At the start of the show, Dr. Nick shared how he got started, and we talked about sex hormone bi