Nature Podcast

00:46 Synthetic cells made from bacterial bitsFor years researchers have been interested in creating artificial cells, as they could be useful for manufacturing compounds and understanding how life works. Now a new method shows how this can be accomplished using polymer droplets that integrate components of burst bacteria. The synthesised cells are able to perform translation and transcription and have several features that resemble real cells, like a proto-nucleus and a cytoskeleton.Research article: Xu et al.News and Views: Life brought to artificial cells09:33 Research HighlightsA mysterious ancient creature identified from its vomit, and the combination of immunity, diet and bacteria that could protect from metabolic disorders.Research Highlight: The Jurassic vomit that stood the test of timeResearch Highlight: A sugary diet wrecks gut microbes — and their anti-obesity efforts11:42 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, research on the safety of three-person embryos,

00:46 Evidence of ancient surgeryA skeleton with an amputated foot discovered in Borneo has been dated to 31,000 years ago, suggesting that complex surgery might be much older than previously thought. The person whose foot was removed survived the procedure, which the researchers behind the find say shows the ‘surgeon’ must have had detailed knowledge of anatomy, and likely had access to antiseptic compounds.Research article: Maloney et al.News and Views: A surgical dawn 31,000 years ago in Borneo10:12 Research HighlightsMummified reptiles hint at severe drought 250 million years ago, and mapping avalanche risk in remote locations.Research Highlight: Quick-dried Lystrosaurus ‘mummy’ holds clues to mass death in the TriassicResearch Highlight: Avalanches in remote peaks are revealed with old satellites’ aid13:09 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, how extreme heat has likely contributed to Pakistan’s devastating floods, and what the James Webb Space Telescope has reveal

The development of brain chimaeras – made up of human and animal neurons – is an area of research that has hugely expanded in the past five years. Proponents say that these systems are yielding important insights into health and disease, but others say the chimeras represent an ethical grey zone, because of the potential to blur the line between humans and other animals, or to recapitulate human-like cognition in an animal.This is an audio version of our Feature: Hybrid brains: the ethics of transplanting human neurons into animals Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

In this episode:00:45 How adding pores helps water carry gasAlthough water is an excellent solvent, it’s limited in its ability to dissolve gasses. To overcome this a team have developed ‘porous water’ containing tiny cages that can hold large numbers of gas molecules. The team suggest that this technology could have multiple medical applications, including in the development of artificial blood.Research article: Erdosy et al.News and Views: Suspended pores boost gas solubility in water11:35 Research HighlightsSynthetic ‘nerves’ help mice to walk, and planets orbiting a star that’s due to go supernova.Research Highlight: Stretchy synthetic nerve helps mice give ball a mighty kickResearch Highlight: A massive planet circles a huge star doomed to explode14:16 When did hominins get on their feet?One of humanity's defining characteristics is our ability to walk on two legs. However, when this ability evolved remains a mystery. A paper out this week suggests that the species Sahelanthropus tchadensis was walking o

00:47 Evidence of a proton’s charmFor decades, scientists have debated whether protons have ‘intrinsic charm’, meaning they contain elementary particles known as charm quarks. Now, using machine learning to comb through huge amounts of experimental data, a team have shown evidence that the charm quark can be found within a proton, which may have important ramifications in the search for new physics.Research article: The NNPDF CollaborationNews and Views: Evidence at last that the proton has intrinsic charm11:26 Research HighlightsHow sea sponges ‘sneeze’ to clean their filters, and why bonobos’ infantile behaviour helps them receive consolation after conflict.Research Highlight: How a sponge ‘sneezes’ mucus: against the flowResearch Highlight: Bonobo apes pout and throw tantrums — and gain sympathy13:52 Briefing ChatWe discuss some highlights from the Nature Briefing. This time, the repeated evolution of the crab body-shape, and why demanding work can lead to mental fatigue.Discover: Evolution Only Thinks Abo

In this first episode of Nature's Take, we get four of Nature's staff around microphones to get their expert take on preprints. These pre-peer-review open access articles have spiked in number over recent years and have cemented themselves as an integral part of scientific publishing. But this has not been without its issues.In this discussion we cover a lot of ground. Amongst other things, we ask whether preprints could help democratise science or contribute to a loss of trust in scientists. We pick apart the relationship between preprints and peer-reviewed journals and tackle some common misconceptions. We ask how preprints have been used by different fields and how the pandemic has changed the game. And as we look to the future, we ask how preprints fit into the discussion around open access and even if they could do away with journals all together. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

Cold exposure in mice activates brown fat to deny tumours glucose, and the future of extreme heatwaves. 00:45 How cold temperatures could starve tumoursA team of researchers have found that exposing mice to the cold could starve tumour cells of the blood glucose they need to thrive. They showed that the cold temperatures deprived the tumours of fuel by activating brown fat – a tissue that burns through glucose to keep body temperature up. The team also showed preliminary evidence of the effect occurring in one person with cancer, but say that more research is needed before this method can be considered for clinical use.Research article: Seki et al.08:59 Research HighlightsEvidence of the world’s southernmost human outpost from before the Industrial Revolution, and how jumping up and down lets canoes surf their own waves.Research Highlight: Bones and weapons show just how far south pre-industrial humans gotResearch Highlight: How jumping up and down in a canoe propels it forwards11:24 The future of extreme hea

00:47 The economic benefits of social connectionsBy looking at data gathered from billions of Facebook friendships, researchers have shown that having more connections with people from higher income groups could increase future incomes by 20%. They also show how such connections can be formed, and how schools and other institutions could help to improve peoples’ opportunities in the future.Research Article: Chetty et al.Research Article: Chetty et al.News and Views: The social connections that shape economic prospectsLink to the data11:06 Research HighlightsHow balloons could help measure quakes on Venus, and the parasitic fungus that tricks flies into mating with fly corpses.Research Highlight: Balloon flotilla detects an earthquake from high in the skyResearch Highlight: The fungus that entices male flies to mate with female corpses13:40 Reviving pig organs hours after deathWhen someone dies, tissues start to irreversibly degrade, but recently this irreversibility has been brought into question by studies s

Inequity has been a central feature of the COVID19 pandemic. From health outcomes to access to vaccines, COVID has pushed long-standing disparities out of the shadows and into the public eye and many of these problems are global. In this episode of Coronapod we dig into a radical new collaboration of 15 countries - co-led by the WHO, and modelled on open-science. The project, called the mRNA vaccine technology transfer hub, aims to create independent vaccine hubs that could supply the global south, and take on the giants of the pharmaceutical industry in the process. But the road ahead is long - the challenges are complex and numerous, and the odds are stacked against them. But at a time when stakes couldn't be higher, momentum is building and if successful, the tantalising possibility of an end to a dangerous legacy of dependence looms. Can it be done? And if so, what needs to change to make it happen? We ask these questions and more.News Feature: The radical plan for vaccine equityThis projec

00:45 Working out how the ability to digest milk spreadHumans have been drinking milk for thousands of years, but it seems that they were doing so long before the ability to digest it became prevalent. Then around 2000 years ago, this ability became common in Europe, presenting a mystery to researchers – why then? Now by analyzing health data, ancient DNA, and fats residues from thousands of ancient pots, scientists have worked out what caused this trait to suddenly spread throughout Europe.Research Article: Evershed et al.News and Views: The mystery of early milk consumption in Europe08:56 Research HighlightsHow genes stolen from outside the animal kingdom have altered insects’ abilities, and a dormant black hole beyond the Milky Way gives insights into these objects' origins.Research Highlight: Genes purloined from across the tree of life give insects a boostResearch Highlight: A quiet black hole whispers its origin story11:21 Assessing the addiction potential for therapeutic ketamineKetamine has shown grea

00:46 When did mammals start to regulate their temperature?The evolution of ‘warm bloodedness’ allowed mammals to live in a more diverse range of habitats, but working out when this occurred has been difficult. To try and pin down a date, researchers have studied the fossilised remains of ancient mammals' inner ears, which suggest that this key evolutionary leap appeared around 230 million years ago.Research Article: Araujo et al.News and Views: Evolution of thermoregulation as told by ear07:14 Research HighlightsA new surgical glue that’s both strong and easy to remove, and southern fin whales return to Antarctica after being hunted to near extinction.Research Highlight: This adhesive bandage sticks strongly — even to hairy skinResearch Highlight: A feeding frenzy of 150 whales marks a species’ comeback09:47 Structure of an enzyme reveals how its so efficientHydrogen dependent CO2 reductase is an enzyme that can convert CO2 from the air into formic acid that can be used as fuel. It also does this extremely e

00:46 A long-term record of climate in the tropicsTo understand the history of the Earth’s climate, researchers often rely on things like ice cores, which contain layered frozen insights of thousands of years of history. However, in the tropics long-term records like these have been absent. Now researchers have uncovered a sediment core in Peru which reveals around 700,000 years of climatic history.Research Article: Rodbell et al.News and Views: Sediment study finds the pulse of tropical glaciers09:40 Research HighlightsThe biological ‘helmets’ that protect shrimp from themselves, and why the colour of wine bottles matters.Research Highlight: ‘Helmets’ shield shrimp from their own supersonic shock wavesResearch Highlight: Why white wine in plain-glass bottles loses its bouquet12:38 The James Webb Space Telescope reveals its first imagesAfter more than two decades of development, the James Webb Space Telescope has broadcast its first images in spectacular detail. We discuss how we got here, what’s next and wha

In this Podcast Extra, Nature's Lizzie Gibney and Federico Levi take a deep-dive into the Higgs boson, describing their experiences of its discovery, what the latest run of the Large Hadron Collider might reveal about the particle's properties, and what role it could play in potential physics beyond the standard model.Nature News: Happy birthday, Higgs boson! What we do and don’t know about the particleNature Editorial: Particle physics isn’t going to die — even if the LHC finds no new particles See acast.com/privacy for privacy and opt-out information.

Since early in the pandemic, scientists have searched for signals of SARS-CoV-2 transmission by sampling wastewater. This surveillance method has provided vital information to inform public health responses. But the approach has never been particularly specific - pointing to broad trends rather than granular information such as which variants are spreading where. But now a team from the University of California have created two new tools to sample waste water in much greater detail - and spot variants and their relative concentrations up to two weeks faster than testing-based surveillance methods. In this episode of Coronapod, we discuss the paper and ask how a system like this could help countries around the world respond to the COVID pandemic and beyond.News: COVID variants found in sewage weeks before showing up in tests See acast.com/privacy for privacy and opt-out information.

00:46 Happy birthday, Higgs boson - looking back at a momentous milestone for physicsTen years ago this week, scientists announced that they’d found evidence of the existence of the Higgs boson, a fundamental particle first theorised to exist nearly sixty years earlier.To celebrate this anniversary, we reminisce about what the discovery meant at the time, and what questions are left to be answered about this mysterious particle.Nature News: Happy birthday, Higgs boson! What we do and don’t know about the particleNature Editorial: Particle physics isn’t going to die — even if the LHC finds no new particles11:09 Research HighlightsClever clothes that can cool or warm the wearer, and finding hidden DNA from the endangered red wolf.Research Highlight: ‘Smart’ clothing flexes to provide relief from the heatResearch Highlight: ‘Ghost’ DNA from the world’s rarest wolves lingers in coyotes13:27 Supporting scientists who stutterStuttering is a speech condition that affects around 70 million people worldwide, which can

In the first episode of our new series Nature hits the books, science journalist Ed Yong joins us to talk about his new book An Immense World, which takes a journey through the weird and wonderful realm of animal senses.In the show, we chat about how our human-centric view of the world has restricted researchers' understanding of animal senses, how to conceptualise what it might be like to be an electric-field sensitive fish, and what bees might make of us blushing...An Immense World, Ed Yong, Random House (2022)Music supplied by Airae/Epidemic Sound/Getty images. See acast.com/privacy for privacy and opt-out information.

00:47 Enteric viruses may spread through salivaEnteric viruses, such as norovirus, cause a significant health burden around the world and are generally considered to only spread via the faecal-oral route. However, new research in mice suggests that saliva may also be a route of transmission for these viruses, which the authors say could have important public health implications.Research Article: Ghosh et al.08:59 Research HighlightsHow devouring space rocks helped Jupiter to get so big, and what analysing teeth has revealed about the diet of the extinct super-sized megalodon shark.Research Highlight: The heavy diet that made Jupiter so bigResearch Highlight: What did megalodon the mega-toothed shark eat? Anything it wanted11:24 Making the tetraneutronFor decades there have been hints of the existence of tetraneutrons, strange systems composed of four neutrons, and now researchers may have created one in the lab. This breakthrough could tell us more about the strong nuclear force that holds matter together.Res

In the next year, no fewer than seven missions are heading to the Moon. While NASA's Artemis programme might be stealing most of the limelight, the United States is just one of many nations and private companies that soon plan to launch lunar missions.Although some of the agencies running these expeditions are providing scant details about the missions, it is hoped the they will provide streams of data about the Moon, heralding what scientists say could be a new golden age of lunar exploration.This is an audio version of our Feature: These six countries are about to go to the Moon — here’s why See acast.com/privacy for privacy and opt-out information.

After a long wait, the US Food and Drug Administration (FDA) and Centres for Disease Control and Prevention (CDC) have finally approved two COVID vaccines for use in children between the ages of six months and five years old. But despite a unanimous decision amongst regulators, parents still have questions about whether to vaccinate their young children, with survey data suggesting that the majority do not intend to accept vaccines right away. In this episode of Coronapod, we dig into the trials, the statistics and the regulators decision making process, in search of clarity around what the data are saying.News: FDA authorizes COVID vaccines for the littlest kids: what the data say See acast.com/privacy for privacy and opt-out information.

00:38 The science of studying inequalityWe discuss the research looking to understand the root causes and symptoms of inequalities, how they are growing, and how a cross-disciplinary approach may be the key to tackling them.Editorial: Equity must be baked into randomized controlled trialsNews Feature: How COVID has deepened inequality — in six stark graphicsCareer Feature: The rise of inequality research: can spanning disciplines help tackle injustice?07:26 The randomised trials helping to alleviate povertyFor decades, researchers have been running randomised trials to assess different strategies to lift people out of poverty. Many of these trials centre on providing people with cash grants – we hear how these trials have fared, efforts to improve on them, and the difficulties of scaling them up.News Feature: These experiments could lift millions out of dire poverty21:23 Why breast cancers metastasize differently at different times of dayA team of researchers have found that breast cancer tumours are more lik